Leptin Resistance: Are you Leptin Resistant ?

leptin resistance

leptin resistance

Are you leptin Resistant?   Let’s find out……….

What is Leptin Resistance ?

Leptin like insulin, is a hormone. It is also known as “fat hormone” or the “obesity hormone”.Leptin is a protein of 167 amino acids and, is secreted by fat cells and is received by receptors in the hypothalamus where the brain’s appetite control centers are located. Leptin is a mediator of long-term regulation of energy balance, suppressing food intake and thereby inducing weight loss.In layman terms, leptin tells your brain when you’ve had enough to eat. Leptin  influences areas of your brain that control the intensity of your desire to eat. It has also been found that leptin not only changes brain chemistry, but can also “rewire” the very important areas of your brain that control hunger and metabolism. The way your body stores fat is a carefully regulated process that is controlled, primarily, by leptin.

What Causes Leptin Resistance?

When the brain is not able to hear the message that you have had enough to eat, your brain thinks you’re starving and will continue to feel hungry. L R can occur when too much circulating leptin which affects the brain’s sensitivity to leptin. The resulting condition leads to a lack of leptin’s appetite-regulating effect and is known as leptin resistance.Research is still exploring whether the problem is in leptin getting to the brain or whether the receptors in the brain have trouble picking up and responding to leptin signaling.

How does Leptin work?

Leptin works by crossing into the brain and binding to specific receptors. When they meet, your body releases chemicals and performs a number of functions, like increasing calorie burning, making your hungry or dulling your want to eat more. The work of leptin receptors, thus, is instrumental in the development of obesity and eating disorders. There are a number of leptin receptors all over your brain, but scientists think the ones involved in eating and energy are located in the hypothalamus.

Who is susceptible to Leptin Resistance (LR)?

You become LR by the same general mechanism that you become insulin-resistant , by continuous overexposure to high levels of the hormone. People can become leptin resistant due to many reasons one of them is eating foods that are processed and loaded with sugar.One possibility is that the receptors of people who are overweight may be lacking these `legs`, so the leptin cannot bind to the brain receptor.Therefore the brain cannot get the message that you are full.

 Leptin Resistance Symptoms:

What happens when you become Leptin resistant?

Overweight people already have a lot of leptin in their system. The problem is their body is not listening to leptin.So, if the cells are not listening to the hormone leptin, it’s the  actually the same as not having leptin at all. And then what happens is  exact the opposite. It takes you a very long time to get full. You’re not full from eating and you just keep eating until you’re stuffed. And the only way that you’re finally full is when your stomach just literally can’t hold any more food.   Also, your tongue loses its sensitivity to sweet foods. So, it takes sweeter foods to satisfy you. Your metabolism slows down because leptin actually does certain things to the thyroid. It has the thyroid secrete certain hormones that speed up your metabolism. If your body’s not listening to leptin, you’re not secreting those hormone.

How to Reverse Leptin Resistance?

  • Consume 30 percent of your daily calories in protein. According to the author of Jillian Michael s  author of ” Master Your Metabolism” , protein improves leptin sensitivity, allowing the person to feel fuller more quickly. Good sources of protein include meat, dairy, legumes and nuts.
  • Take an Omega-3 supplement which increases leptin by production of glucose.
  • Add more zinc to your diet.Zinc like omega-3 increases leptin levels.Natural sources of zinc are, red meat,whole grain, oysters.
  • Avoid fasting or yo-yo dieting.According to Dr. John Berardi, who specializes in nutrient biochemistry and exercise biology, people who fasted for 36 hours experienced a 77 percent decrease in leptin.
  • People who exercise regularly have high levels of leptin sensitivity.




 Dr Mercola



Jillian Michaels,”Master your Metabolism”










Related Posts Plugin for WordPress, Blogger...


Leave a Reply

Wordpress SEO Plugin by SEOPressor